发明名称 SUBSTANCE AND METHOD FOR TREATING INFLUENZA
摘要 A composition and method for treatment and protecting against influenza that includes bioactive Substance P and/or its analogs. The composition agents can be administered via inhalation therapy, intravenously, intramuscularly, sublingually, or by other methods.
申请公布号 US2017065663(A1) 申请公布日期 2017.03.09
申请号 US201515308556 申请日期 2015.05.04
申请人 Wilhelm Michael K.;Romano Christopher A. 发明人 Wilhelm Michael K.;Romano Christopher A.
分类号 A61K38/04;A61K9/00;A61K45/06 主分类号 A61K38/04
代理机构 代理人
主权项 1. A composition for preventing or ameliorating the onset of one or more symptoms of influenza, the composition comprising: an effective amount of a substance P compound; a carrier medium, wherein the carrier medium is one of an aqueous solution, a food grade organic liquid, an inert food grade solid and wherein the substance P compound is present in the carrier medium in an amount sufficient to provide a dose strength between 0.05 nanomolar and 10 micromolar, effective to trigger reduction of a symptom from a group including at least one of the following: neutrophil number, alveolar-capillary barrier membrane damage, pulmonary inflammation, weight loss, viral titers, mortality, fever, myalgia, wherein the substance P compound is a derivative of substance P selected from the group consisting of; Sar9, Met (O2)11-Substance P; [Met-OH11]-substance P; [Met-OMe11]-substance P; [Nle11]-substance P; [Pro9]-substance P; [Sar9]-substance P; [Tyr8]-substance P; [p-Cl-Phe7,8]-substance P.
地址 Scottsdale AZ US