| 摘要 |
The present invention provides methods for determining in a subject suffering from either type 1 diabetes mellitus or type 2 diabetes mellitus the risk of developing, and/or the rate of progression of certain diabetes associated complications (e.g., diabetic nephropathy and other associated disorders) resulting from angiopathic changes in the subject such as microvascular and/or macrovascular damage. The present invention also provides methods for handling, storing, and preserving, biological samples (e.g., blood, plasma, urine) from a subject having either Type 2 or Type 1 diabetes. Further provided are methods for analyzing biological samples from a subject to determine the quantities of one or more biomarkers of interest in comparison to results obtained from previous samples from the subject and/or to results obtained from aggregated samples, or to standards. Further provided are materials that will allow health care professionals to improve diabetes management in a subject or group of subjects based upon analysis of the risks of developing, and/or the rates of progression of certain diabetes associated complications. |
