Antisense oligonucleotides directed against connective tissue growth factor and uses thereof
摘要
Abstract This invention provides compounds which comprise modified oligonucleotides capable of inhibitory expression of connective tissue factor and composition containing same as well as methods of treating hyperprolific disorders and fibrotic diseases, and of reducing scarring resulting from wound healing using such compounds.
申请公布号
AU2010224447(B2)
申请公布日期
2017.03.09
申请号
AU20100224447
申请日期
2010.09.28
申请人
Excaliard Pharmaceuticals, Inc.;Ionis Pharmaceuticals, Inc.
发明人
Bennett, C. Frank;Foulkes, J. Gordon;O'Donnell, Niall;Dean, Nicholas M.;Frier, Susan M.