发明名称 |
LIVE ATTENUATED EDWARDSIELLA ICTALURI VACCINE AND METHOD OF USING THE SAME |
摘要 |
A live attenuated Edwardsiella ictaluri bacterium lacking a viable gene encoding a functional evpB protein and a method of using the same to protect fish against infection from virulent Edwardsiella ictaluri. The methods and compositions for protecting fish against infection from virulent Edwardsiella ictaluri comprising administering to a fish a therapeutically effective amount of an attenuated Edwardsiella ictaluri bacterium lacking a viable gene encoding a functional EvpB protein. The bacterium may include an insertion and/or deletion mutation in the evpB gene. The fish include catfish, preferably catfish fingerling or a catfish fry. The composition may be delivered via immersion delivery, an injection delivery, an oral delivery, or combinations thereof. |
申请公布号 |
US2017065695(A1) |
申请公布日期 |
2017.03.09 |
申请号 |
US201615257607 |
申请日期 |
2016.09.06 |
申请人 |
Karsi Attila;Lawrence Mark L.;Abdelhamed Hossam |
发明人 |
Karsi Attila;Lawrence Mark L.;Abdelhamed Hossam |
分类号 |
A61K39/02;C12N1/20 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
1. An attenuated Edwardsiella ictaluri bacterium, the bacterium lacking a viable gene encoding a functional EvpB protein. |
地址 |
Starkville MS US |