SUBSTITUTED 2-[3-(1-METHYL-PIPERIDIN-4-YL)-PROPYLAMINO]-PYRIMIDINE-5-CARBOXYLIC ACIDS AND AMIDES AND METHODS OF MAKING THE SAME

摘要

The present invention relates to certain intermediates useful in the preparation of certain benzoimidazol-2-yl pyrimidines and processes for preparing them. In particular, the present invention relates to various 2-[3-(1-methyl-piperidin-4-yl)-propylamino]-pyrimidine-5-carboxylic acids and amides as useful intermediates in the preparation of compounds including;

主权项

1. A compound having a structure of Formula (VI) wherein
R1 is H or C1-6 alkyl;each R2 is independently H, chloro, fluoro, or C1-6 alkyl;each R3 is C1-6 alkyl or an amine protecting group; andn is 1, 2, 3, or 4.