发明名称 |
ENZYMATICALLY RESPONSIVE MAGNETIC PARTICLES AND THEIR USE |
摘要 |
The invention relates to an enzymatically responsive product that includes an amino acid residue conjugated to a magnetic particle, wherein the amino acid residue is phosphorylated or sulfated or comprises an ester-moiety linked via peptide bond. Compositions containing the enzymatically responsive product, and the use thereof for separating distinct types of mammalian cells (e.g., cancer cells from normal cells), for treating a cancerous condition, and imaging cancer cells are also disclosed. |
申请公布号 |
US2017119910(A1) |
申请公布日期 |
2017.05.04 |
申请号 |
US201515303117 |
申请日期 |
2015.04.09 |
申请人 |
BRANDEIS UNIVERSITY |
发明人 |
DU Xuewen;ZHOU Jie;XU Bing |
分类号 |
A61K49/18;A61K45/06;G01N33/574;A61K38/08;A61K41/00 |
主分类号 |
A61K49/18 |
代理机构 |
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代理人 |
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主权项 |
1. A product comprising an amino acid residue conjugated to a magnetic particle, wherein the amino acid residue is phosphorylated or sulfated or comprises an ester-moiety linked via peptide bond. |
地址 |
Waltham MA US |