Controller for an acoustic standing wave generation device in order to prevent clogging of a filter

摘要

The invention relates to a method and apparatus to continuously monitor and control acoustic energy and vacuum pressure to maintain a net unidirectional flow of multi-phase heterogeneous fluids through a porous filter or membrane. The heterogeneous fluid may come form a variety of sources including biological sources such as, blood, bone marrow aspirate (BMA), adipose tissue (lipoaspirate), urine, saliva, etc.

主权项

1. An apparatus for separating a fraction from a fluid sample, the apparatus comprising:
a filtration unit including at least one filter which divides the filtration unit into a prefiltration chamber for receiving the fluid sample and a post-filtration chamber for receiving a filtrate of the fluid sample; the filter movable from a horizontal orientation to a tilted orientation; a fluid barrier abutting a porous top surface of the filter; the filter configured to form a pool area on a lowered portion of the porous surface against the fluid barrier when the filter is in the tilted orientation; and a filter tilting device coupled to the filter and configured to tilt the filter from the horizontal orientation to the tilted orientation.