| 发明名称 |
CHIMERIC POST-TRANSCRIPTIONAL REGULATORY ELEMENT |
| 摘要 |
The present disclosure relates to chimeric post-transcriptional regulatory elements (PRE) and vectors useful for expressing a protein in a cell. The PRE contains alpha, beta and optionally gamma subelements selected from different native PRE sequences and are discovered to be more potent than their native counterparts. |
| 申请公布号 |
US2017114363(A1) |
申请公布日期 |
2017.04.27 |
| 申请号 |
US201615335930 |
申请日期 |
2016.10.27 |
| 申请人 |
Celltheon Corporation |
发明人 |
Goel Nikhil;Goel Amita |
| 分类号 |
C12N15/85;C07K16/28 |
主分类号 |
C12N15/85 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A polynucleotide comprising:
(a) a first fragment consisting of the nucleic acid sequence of SEQ ID NO: 14 or a nucleic acid sequence having at least 95% sequence identity to SEQ ID NO: 14, and (b) a second fragment consisting of the nucleic acid sequence of SEQ ID NO: 3 or a nucleic acid sequence having at least 95% sequence identity to SEQ ID NO: 3. |
| 地址 |
Union City CA US |
