发明名称 Collapsible prosthetic valve
摘要 A prosthetic valve is provided for implantation in a stenosed aortic valve. The prosthetic valve includes a radially collapsible frame configured for advancement through a patient's vasculature using a catheterization technique. A collapsible valvular structure is sewn to the frame for permitting blood to flow in only one direction. An internal cover extends along an internal surface of the frame. The internal cover forms a tubular sleeve positioned between a lower extremity of the frame and the valvular structure. The internal cover prevents the passage of blood through spaces between bars of the frame. An upper end of the internal cover is sutured to the valvular structure. The internal cover is preferably made of pericardium.
申请公布号 US9629714(B2) 申请公布日期 2017.04.25
申请号 US201514805179 申请日期 2015.07.21
申请人 Edwards Lifesciences PVT, Inc. 发明人 Letac Brice;Cribier Alain
分类号 A61F2/24;A61B90/00 主分类号 A61F2/24
代理机构 Klarquist Sparkman LLP 代理人 Klarquist Sparkman LLP
主权项 1. A prosthetic valve for implantation in a native aortic valve, comprising: a frame comprising a plurality of intersecting wires, the frame having an upper extremity, a lower extremity, an external surface and an internal surface, the frame being compressible to a compressed external diameter suitable for introduction into a femoral artery by a transcutaneous catheterization technique, the frame being expandable for implantation in the native aortic valve; a collapsible valvular structure supported inside the frame, the valvular structure having an open state and a closed state for permitting blood to flow in one direction, wherein the valvular structure has an inlet end fastened to the frame along a fastening line that extends along a circumference of the inlet end, the inlet end defines an annular shape in a plane that is perpendicular to a central axis of the frame, wherein the valvular structure comprises a truncated hyperboloidal shape having a concave outer surface toward the aortic wall when the valvular structure is in the open state and the prosthetic valve is implanted in the native aortic valve, wherein the valvular structure has an outlet opening in the open state having a diameter that is smaller than a diameter of an inlet opening of the valvular structure; and a plurality of elongated struts connected to the valvular structure inside of the frame to induce a patterned movement of the valvular structure between the open state and the closed state, the elongated struts extending lengthwise of the frame in a direction from the lower extremity to the upper extremity.
地址 Irvine CA US