发明名称 Compositions for the treatment of hypertension and/or fibrosis
摘要 The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of hypertension and/or fibrosis.
申请公布号 US9630935(B2) 申请公布日期 2017.04.25
申请号 US201415022264 申请日期 2014.09.17
申请人 VECTUS BIOSYSTEMS LIMITED 发明人 Duggan Karen Annette
分类号 C07D263/58;C07C311/08;C07C275/42;C07C237/20;C07D213/89;C07C255/61;C07D213/74;C07D215/02;C07C271/28;C07D231/56;C07C307/10;C07C311/03;C07D235/04;C07D249/18;C07C235/34;C07D263/54;C07D209/18;C07D277/62;C07C261/04;C07D209/08;C07D209/34;C07D215/227;C07D235/08;C07D235/10;C07D235/26;C07D277/68 主分类号 C07D263/58
代理机构 代理人 Van Amsterdam John R.
主权项 1. A compound of the formulawherein: A is selected from the group consisting of: Q is independently selected from halo, alkyl, hydroxy, amino and substituted amino; n is 0, 1, 2, 3, 4 or 5; R1, R3 and R4 are independently C, CH, CH2, O, N, NH or S, and R2 is C, CH, CH2, N, NH, C—CF3, CH—CF3 or C═O, or a stereoisomer or pharmaceutically acceptable salt thereof, wherein when n is 1, Q cannot be hydroxy.
地址 Rosebery AU