发明名称 AQUEOUS OPHTHALMIC COMPOSITION
摘要 An aqueous ophthalmic composition is provided comprising at least one component which is selected from the group consisting of a polysaccharide, a monosaccharide, at least one vitamin component selected from the group consisting of vitamin B12, vitamin B2, vitamin A and panthenol, at least one oil component selected from the group consisting of a plant oil, an animal oil and a mineral oil, at least one surfactant selected from the group consisting of polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil, polyoxyethylene polyoxypropylene glycol and polyoxyl stearate, an anti-allergic component, a preservative, a thickening component, a polyhydric alcohol, an anti-inflammatory component, an anti-bacterial agent and a cooling and/or refreshing agent; and (B) a buffering agent. When the composition is brought into contact with a polybutylene terephthalate-containing resin container, the container can be prevented from weight change, deterioration and wetting and can be improved in a liquid cutting property.
申请公布号 US2017105934(A1) 申请公布日期 2017.04.20
申请号 US201515317851 申请日期 2015.06.09
申请人 ROHTO Pharmaceutical Co., Ltd. 发明人 Mizutare Yoko;Matsumura Yasuko
分类号 A61K9/08;A61K47/12;A61K47/10;A61K47/18;A61K47/02;A61K9/00;A61K47/26 主分类号 A61K9/08
代理机构 代理人
主权项 1. An aqueous ophthalmic composition, comprising (A) at least one surfactant selected from the group consisting of polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil, polyoxyethylene polyoxypropylene glycol, polyoxyl stearate, and polysorbate 80; at least one cooling and/or refreshing agent of 0.015-0.1 w/v % selected from the group consisting of eucalyptus oil and bergamot oil, and menthol; and (B) a buffering agent; wherein (C) the aqueous ophthalmic composition is held in a container in which a part of a surface or the whole surface that is brought into contact with the aqueous ophthalmic composition is molded with a resin containing polybutylene terephthalate.
地址 Osaka JP