Carotenoid oil suspension with high bioavailability and preparation method thereof

摘要

A carotenoid oil suspension and preparation method thereof are provided. The method includes the following steps: a) mixing carotenoid with organic solvent, heating the mixture to dissolve the carotenoid sufficiently to obtain carotenoid solution; b) introducing the carotenoid solution obtained in step a) into a vegetable oil solution stirred in high speed by spraying, meanwhile recovering the organic solvent generated during spraying under vacuum condition, then, simultaneously completing recycling and spraying, thereafter, obtaining carotenoid oil suspension; wherein, the carotenoid oil suspension comprises a carotenoid crystal with an average particle size of less than 5 μm. The method is applicable in industrial scale with continuous operation and increased efficiency without additional carotenoid crystal grinding processes, and decreases the degradation of carotenoid during the preparation process of carotenoid oil suspension.

主权项

1. A method of preparing a carotenoid oil suspension comprising the steps of:
a) mixing a carotenoid with an organic solvent to obtain a mixture, heating the mixture at a temperature to sufficiently dissolve the carotenoid to obtain a carotenoid solution; and b) introducing the carotenoid solution obtained in step a) into a vegetable oil solution under a high speed stirring by spraying, and in the meantime recovering the organic solvent generated during spraying under vacuum condition, then simultaneously completing recovering and spraying, thereafter, obtaining a carotenoid oil suspension; wherein the carotenoid oil suspension comprises a carotenoid crystal with an average particle size of less than 5 μm, and the organic solvent is a water-soluble organic solvent or water-insoluble organic solvent.