发明名称 |
Single-chain variable fragment anti-CD133 antibodies and uses thereof |
摘要 |
Disclosed herein are a monoclonal antibody that specifically binds to human CD133 and single-chain variable fragments thereof. Also disclosed herein is a hybridoma that produces the monoclonal antibody that specifically binds to human CD133. |
申请公布号 |
US9624303(B2) |
申请公布日期 |
2017.04.18 |
申请号 |
US201614990501 |
申请日期 |
2016.01.07 |
申请人 |
Regents of the University of Minnesota |
发明人 |
Ohlfest John R.;Panyam Jayanth;Swaminathan Suresh Kumar;Vallera Daniel A. |
分类号 |
C07K16/28;A61K39/00;C07K16/30 |
主分类号 |
C07K16/28 |
代理机构 |
Mueting, Raasch & Gebhardt, PA |
代理人 |
Mueting, Raasch & Gebhardt, PA |
主权项 |
1. An isolated polynucleotide comprising a nucleotide sequence that encodes the amino acid sequence of SEQ ID NO:47, SEQ ID NO:48, SEQ ID NO:49, SEQ ID NO:50, SEQ ID NO:51, SEQ ID NO:52, SEQ ID NO:53, SEQ ID NO:54, SEQ ID NO:55, or SEQ ID NO:58. |
地址 |
Minneapolis MN US |