发明名称 Single-chain variable fragment anti-CD133 antibodies and uses thereof
摘要 Disclosed herein are a monoclonal antibody that specifically binds to human CD133 and single-chain variable fragments thereof. Also disclosed herein is a hybridoma that produces the monoclonal antibody that specifically binds to human CD133.
申请公布号 US9624303(B2) 申请公布日期 2017.04.18
申请号 US201614990501 申请日期 2016.01.07
申请人 Regents of the University of Minnesota 发明人 Ohlfest John R.;Panyam Jayanth;Swaminathan Suresh Kumar;Vallera Daniel A.
分类号 C07K16/28;A61K39/00;C07K16/30 主分类号 C07K16/28
代理机构 Mueting, Raasch & Gebhardt, PA 代理人 Mueting, Raasch & Gebhardt, PA
主权项 1. An isolated polynucleotide comprising a nucleotide sequence that encodes the amino acid sequence of SEQ ID NO:47, SEQ ID NO:48, SEQ ID NO:49, SEQ ID NO:50, SEQ ID NO:51, SEQ ID NO:52, SEQ ID NO:53, SEQ ID NO:54, SEQ ID NO:55, or SEQ ID NO:58.
地址 Minneapolis MN US