| 发明名称 |
HUMAN ANTI IL-6 ANTIBODIES WITH EXTENDED IN VIVO HALF-LIFE AND THEIR USE IN TREATMENT OF ONCOLOGY, AUTOIMMUNE DISEASES AND INFLAMMATORY DISEASES |
| 摘要 |
The present invention provides human anti-IL-6 antibodies with extended in vivo half-life. The invention further relates to pharmaceutical compositions, therapeutic compositions, and methods using therapeutic antibodies that bind to IL-6 and that has an extended in vivo half-life for the treatment and prevention of IL-6 mediated diseases and disorders, such as, but not limited to, inflammatory diseases and disorders, autoimmune diseases and disorders and tumors. |
| 申请公布号 |
US2017101468(A1) |
申请公布日期 |
2017.04.13 |
| 申请号 |
US201615368499 |
申请日期 |
2016.12.02 |
| 申请人 |
MedImmune Limited |
发明人 |
Bowen Michael;Wu Herren;Dall'Acqua William;Kiener Peter;Jallal Bahija;Coyle Anthony |
| 分类号 |
C07K16/24 |
主分类号 |
C07K16/24 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated antibody that specifically binds to IL-6, wherein the antibody comprises the amino acid sequences of SEQ ID NO: 9 and SEQ ID NO: 10. |
| 地址 |
Cambridge GB |
