发明名称 Method and System for Preventing Migraine Headaches, Cluster Headaches and Dizziness
摘要 A method and system for addressing the avoidance of migraines, cluster headaches and dizziness by adjusting an individual's microbiome, and in particular, to the provision of beneficial oral and gut microbes at particular times to enhance a person's oral health, including through the use of oral strips that adhere to surfaces in the oral cavity.
申请公布号 US2017100329(A1) 申请公布日期 2017.04.13
申请号 US201615384716 申请日期 2016.12.20
申请人 Kovarik Joseph E.;Kovarik Katherine Rose 发明人 Kovarik Joseph E.;Kovarik Katherine Rose
分类号 A61K9/00;A61K39/395;C07K16/28;A61M31/00;A61K35/747;A61K45/06;A61K31/047;A61K35/74;A61K35/741 主分类号 A61K9/00
代理机构 代理人
主权项 1. A method of reducing the likelihood of migraine headaches, comprising: providing to an individual in need thereof a buccal bioadhesive strip, said strip having a first and second side, said first side having a surface comprising a pattern defined by a plurality of spaced apart features each having at least one microscale dimension and having at least one neighboring feature having a substantially different geometry, wherein an average spacing between adjacent ones of said features is between 0.5 and 5 .mu.m in at least a portion of said surface, the second side having a bioadhesive that is adapted to bind to a mucosal membrane for at least 1 hour while inside a person's mouth, wherein said strip includes xylitol and at least one encapsulated feature containing a bacteria selected from the group consisting of Lachnospira, Veillonella, Faecalibacterium and Rothia.
地址 Englewood CO US