Pressure-regulating vial adaptors

摘要

In certain embodiments, a vial adaptor comprises a housing configured to couple the adaptor with a vial, an access channel, a regulator channel, and a regulator assembly. The access channel is configured to facilitate withdrawal of fluid from the vial when the adaptor is coupled to the vial. The regulator channel is configured to facilitate a flow of a regulating fluid from the regulator assembly to compensate for changes in volume of a medical fluid in the vial. In some embodiments, the regulator assembly includes a flexible member configured to expand and contract in accordance with changes in the volume of the medical fluid in the vial. In some embodiments, the flexible member is substantially free to expand and contract. In some embodiments, the flexible member is not partly or completely located in a rigid enclosure.

主权项

1. A medical adaptor capable of coupling with a sealed container, the medical adaptor comprising:
a housing comprising:
a medical connector interface;an access channel capable of conveying medicinal fluid from a sealed container and extending between the medical connector interface and a distal access port; anda regulator channel comprising a distal passageway, a regulator valve, and a proximal passageway, the distal passageway extending from the regulator valve to a distal regulator aperture; and a regulator assembly in fluid communication with the proximal passageway, the regulator assembly comprising;
a regulator nest having a storage volume; anda flexible enclosure in fluid communication with the proximal passageway, the flexible enclosure capable of transitioning between a stored configuration wherein the flexible enclosure is positioned within the regulator nest and a deployed configuration wherein at least a portion of the flexible enclosure is positioned outside of the regulator nest, the flexible enclosure having a stored volume when in the stored configuration and a deployed volume when in the deployed configuration, the flexible enclosure having a stored width when in the stored configuration and a deployed width when in the deployed configuration that is different from the stored width; wherein the deployed volume of the flexible enclosure is at least 500% greater than the storage volume of the regulator nest.