Advanced functional biocompatible polymer putty used as a hemostatic agent for treating damaged tissue and cells

摘要

A hemostatic putty for treatment of a variety of wounds topographies, including but not limited to highly three dimensional wounds, for example gunshot wounds and impalements, is disclosed. The putty is comprised of a matrix polymer weakly crosslinked or not crosslinked such that a viscoelastic matrix is formed. The viscoelastic nature of the putty is tunable by the composition and enables the putty to conform to a variety of wound topographies. Likewise, a hemostatic polymer, for example chitosan or hydrophobically modified chitosan, is included in this matrix to impart hemostatic properties and tissue adhesive on the putty. The hemostatic polymers disclosed prevent microbial infection and are suitable for oxygen transfer required during normal wound metabolism.

主权项

1. A putty, comprising:
a hemostatic biopolymer comprising hydrophobically modified chitosan, polyvinyl alcohol as a secondary polymer, a borate salt ionic crosslinker, and a solvent.