发明名称 Dicarboxylic acid compound
摘要 It is an object of the present invention to provide a medicament for preventing or treating hyperphosphatemia. Solution: A compound represented by a general formula (I) or a pharmacologically acceptable salt thereof. [In the formula, R1: a methyl group or the like, R2: a hydrogen atom or the like, R3: a hydrogen atom or the like, A: a cyclohexyl ring or the like, X: CH or the like, Y: CH or the like, Z: CH or the like, and n: 2 or the like].
申请公布号 US9617232(B2) 申请公布日期 2017.04.11
申请号 US201414784187 申请日期 2014.04.23
申请人 DAIICHI SANKYO COMPANY, LIMITED 发明人 Uto Yoshikazu;Kato Mikio;Takahashi Hidenori;Ogawa Yasuyuki;Iwamoto Osamu;Kono Hiroko;Aoki Kazumasa
分类号 A61K31/196;C07D213/75;A61P3/00;A61K31/40;A61K31/4545;C07D213/82;C07D295/14;A61K31/451;A61P7/00;C07C311/20;C07D295/155 主分类号 A61K31/196
代理机构 Foley & Lardner LLP 代理人 Foley & Lardner LLP
主权项 1. A compound of general formula (I) or a pharmacologically acceptable salt thereof, or a hydrate of the compound or pharmacologically acceptable salt thereof: wherein each substituent is as defined below: R1: a C1-6 alkyl group, a C1-6 alkoxy C1-6 alkyl group, a C3-6 cycloalkyl group, or a C3-6 cycloalkyl C1-6 alkyl group, R2: a hydrogen atom or a halogen group, R3: a hydrogen atom, a halogen group, a halogeno C1-6 alkyl group, a halogeno C1-6 alkoxy group, a C2-5 saturated cyclic amino group, a C1-6 dialkylamino group, a C3-6 cycloalkyl C1-6 alkoxy group, or a C1-6 alkoxy group, A: a C3-6 cycloalkyl ring, X: CH or N, Y: CH or N, Z: CH or N, and n: an integer selected from 1, 2, 3, and 4.
地址 Tokyo JP