发明名称 |
PHARMACEUTICAL COMPOSITIONS OF 3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL) CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIODIN-2-YL)BENZOIC ACID AND ADMINISTRATION THEREOF |
摘要 |
A pharmaceutical composition comprising Compound 1, (3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid), and at least one excipient selected from: a filler, a diluent, a disintegrant, a surfactant, a binder, a glidant and a lubricant, the composition being suitable for oral administration to a patient in need thereof to treat a CFTR mediated disease such as Cystic Fibrosis. Methods for treating a patient in need thereof include administering an oral pharmaceutical formulation of Compound 1 to the patient. |
申请公布号 |
EP3150198(A1) |
申请公布日期 |
2017.04.05 |
申请号 |
EP20160185289 |
申请日期 |
2011.04.07 |
申请人 |
Vertex Pharmaceuticals Incorporated |
发明人 |
VERWIJS, Marinus, Jacobus;ALARGOVA, Rossitza, Gueorguieva;KAUSHIK, Ritu, Rohit;KADIYALA, Irina, Nikolaevna;YOUNG, Christopher, Ryan |
分类号 |
A61K9/16;A61K9/20;A61K9/28;C07D213/75;C07D405/12;C07D405/14 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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