Surgical applications for BMP binding protein

摘要

The present invention relates to the clinical application of BBP, alone or in combination with other growth factors, for use in bone healing applications, such as spinal surgery. Additional applications include use in orthopedic implantable prostheses and implantation into other surgical sites (e.g., surgical reconstruction, regional osteopenia, etc.) where bone is desired.

主权项

1. An article of manufacture comprising an implant, including a peptide having the amino acid sequence of SEQ ID No. 11, or a fragment thereof, wherein said peptide or fragment induces calcification in vertebrates.