发明名称 Combination neisserial compositions
摘要 Compositions comprising a first biological molecule from a Neisseria bacterium and a second biological molecule from a Neisseria bacterium. The term “biological molecule” includes proteins and nucleic acids. Preferred Neisseria species are N. meningitidis and N. gonorrhoeae.
申请公布号 US9610342(B2) 申请公布日期 2017.04.04
申请号 US201615015004 申请日期 2016.02.03
申请人 GlaxoSmithKline Biologicals SA 发明人 Giuliani Marzia Monica;Pizza Mariagrazia;Rappuoli Rino
分类号 A61K39/095;C07K14/00;C07K14/22;A61K38/16;A61K39/39;A61K39/02;A61K39/00 主分类号 A61K39/095
代理机构 Morrison & Foerster LLP 代理人 Morrison & Foerster LLP
主权项 1. A composition comprising (a) an immunologically effective amount of a protein having the amino acid sequence of the mature form of SEQ ID NO: 3518 lacking amino acids 1-19 of SEQ ID NO: 3518 and lacking an N-terminal cysteine at position 20 of SEQ ID NO: 3518; (b) an immunologically effective amount of an N. meningitidis protein comprising an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 7645, and (c) an effective amount of an adjuvant.
地址 Rixensart BE