发明名称 |
Combination neisserial compositions |
摘要 |
Compositions comprising a first biological molecule from a Neisseria bacterium and a second biological molecule from a Neisseria bacterium. The term “biological molecule” includes proteins and nucleic acids. Preferred Neisseria species are N. meningitidis and N. gonorrhoeae. |
申请公布号 |
US9610342(B2) |
申请公布日期 |
2017.04.04 |
申请号 |
US201615015004 |
申请日期 |
2016.02.03 |
申请人 |
GlaxoSmithKline Biologicals SA |
发明人 |
Giuliani Marzia Monica;Pizza Mariagrazia;Rappuoli Rino |
分类号 |
A61K39/095;C07K14/00;C07K14/22;A61K38/16;A61K39/39;A61K39/02;A61K39/00 |
主分类号 |
A61K39/095 |
代理机构 |
Morrison & Foerster LLP |
代理人 |
Morrison & Foerster LLP |
主权项 |
1. A composition comprising
(a) an immunologically effective amount of a protein having the amino acid sequence of the mature form of SEQ ID NO: 3518 lacking amino acids 1-19 of SEQ ID NO: 3518 and lacking an N-terminal cysteine at position 20 of SEQ ID NO: 3518; (b) an immunologically effective amount of an N. meningitidis protein comprising an amino acid sequence having at least 95% sequence identity to SEQ ID NO: 7645, and (c) an effective amount of an adjuvant. |
地址 |
Rixensart BE |