发明名称 |
ADENOSINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, CONTAINING SAME AS ACTIVE INGREDIENT |
摘要 |
The present invention relates to: an adenosine derivative; a preparation method therefor; and a pharmaceutical composition for preventing or treating cancer, containing the same as an active ingredient. According to the present invention, the adenosine derivative has high affinity and selectivity as an A3 adenosine receptor agonist, and exhibits remarkably excellent tumor growth inhibition efficacy in a cancer cell transplanted nude mouse experimental animal model using liver cancer cell SK-HEP-1, in comparison with a conventionally known A3 adenosine receptor agonist, thereby being useful as a pharmaceutical composition for preventing or treating cancer. |
申请公布号 |
WO2017052322(A1) |
申请公布日期 |
2017.03.30 |
申请号 |
WO2016KR10746 |
申请日期 |
2016.09.26 |
申请人 |
FUTURE MEDICINE CO., LTD. |
发明人 |
JEONG, Lak Shin;LEE, Sang Kook;YU, Jin Ha |
分类号 |
C07D473/34;A23L33/10;A61K31/095;A61K31/52;C07D345/00 |
主分类号 |
C07D473/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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