发明名称 NOVEL BRANCHED AMPHIPHILIC LIPIDS
摘要 The invention relates to novel branched amphiphilic lipids. The invention specifically relates to novel branched amphiphilic lipids of general formula (II). The invention also relates to a method of synthesis for said compounds of formula (II), from unsaturated amphiphilic compounds of general formula (I). The invention further relates to the use of the compounds of general formula (II) and lipoplexes obtained by formulation of the compounds of general formula (II) for applications, particularly transfection, in which improved fusion properties are desired.
申请公布号 WO2017051129(A1) 申请公布日期 2017.03.30
申请号 WO2016FR52410 申请日期 2016.09.23
申请人 UNIVERSITÉ DE BRETAGNE OCCIDENTALE;INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE);CENTRE HOSPITALIER RÉGIONAL ET UNIVERSITAIRE DE BREST 发明人 JAFFRÈS, Paul-Alain;COUTHON-COURVÈS, Hélène;AFONSO, Damien;MONTIER, Tristan;LE GALL, Tony
分类号 C07F9/24;A61K9/127;A61K47/00 主分类号 C07F9/24
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