| 发明名称 |
Asymmetric synthesis of a substituted pyrrolidine-2-carboxamide |
| 摘要 |
The present invention provides an improved method for the large scale production of the compound 4-{[(2R,3S,4R,5S)-3-(3-chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino}-3-methoxy-benzoic acid. |
| 申请公布号 |
AU2014220865(B2) |
申请公布日期 |
2017.03.30 |
| 申请号 |
AU20140220865 |
申请日期 |
2014.02.18 |
| 申请人 |
F. Hoffmann-La Roche AG |
发明人 |
Fishlock, Daniel;Gu, Chen;Shu, Lianhe;Sarma, Keshab;Rege, Pankaj Devdatta |
| 分类号 |
C07D207/16 |
主分类号 |
C07D207/16 |
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