| 发明名称 |
EXPRESSION OF VOLTAGE-GATED ION CHANNELS IN CILIATES |
| 摘要 |
Methods are disclosed for the production of mammalian voltage-gated ion channels in ciliates. In other aspects, compositions comprising lipid bilayers containing mammalian voltage-gated ion channels are disclosed. In other aspects, compositions comprising purified and reconstituted mammalian voltage-gated ion channels are disclosed. |
| 申请公布号 |
US2017089921(A1) |
申请公布日期 |
2017.03.30 |
| 申请号 |
US201515306869 |
申请日期 |
2015.05.05 |
| 申请人 |
Tetragenetics, Inc. |
发明人 |
COLUSSI Paul;PAPOYAN Ashot;BISHARYAN Yelena;BEDNENKO Janna;CLARK Theodore G. |
| 分类号 |
G01N33/68;C07K16/00;G01N33/92;C07K1/00;C12N1/10;C12N15/79 |
主分类号 |
G01N33/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A transgenic ciliate comprising:
a transgene encoding a mammalian voltage-gated ion channel operably joined to regulatory sequences such that the ciliate expresses the voltage-gated ion channel protein. |
| 地址 |
Arlington MA US |
