Compounds and compositions for modulating EGFR mutant kinase activities
摘要
The present invention provides a new group of protein kinase inhibitors, aminopyrimidine derivatives, and pharmaceutically acceptable salts thereof that are useful for treating cell proliferative disease and disorder such as cancer and immune disease. The present invention provides methods for synthesizing and administering the protein kinase inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the protein kinase inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefore. The invention also provides useful intermediates generated during the syntheses of the aminopyrimidine derivatives.
申请公布号
AU2015331166(A1)
申请公布日期
2017.03.30
申请号
AU20150331166
申请日期
2015.10.13
申请人
Yuhan Corporation
发明人
Suh, Byung-Chul;Salgaonkar, Paresh Devidas;Lee, Jaekyoo;Koh, Jong Sung;Song, Ho-Juhn;Lee, In Yong;Lee, Jaesang;Jung, Dong Sik;Kim, Jung-Ho;Kim, Se-Won