The present invention provides compositions comprising a Fc-containing protein wherein substantially all the Fc domains have a C-terminal lysine. Further provided are host cell for producing said compositions, methods of making said host cells and compositions, and method of use thereof.
申请公布号
WO2017053482(A1)
申请公布日期
2017.03.30
申请号
WO2016US52962
申请日期
2016.09.21
申请人
GENENTECH, INC.;F. HOFFMANN-LA ROCHE AG
发明人
HALEY, Benjamin;HU, Zhilan;JOLY, John, C.;SHEN, Amy, Y.;SNEDECOR, Bradley, Richard