Contemplated methods and devices comprise use of a charged probe and a pseudoligand in the electrochemical detection of a wide range of analytes, including nucleic acids, proteins and small molecules. In certain embodiments, the pseudoligand forms a complex with the probe that has a reduced charge magnitude compared to the probe itself, and is displaced from the probe when the complex is exposed to the analyte.
申请公布号
EP3147372(A2)
申请公布日期
2017.03.29
申请号
EP20160185746
申请日期
2012.11.21
申请人
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO