| 发明名称 |
LIPID MEMBRANE STRUCTURE FOR siRNA INTRACELLULAR DELIVERY |
| 摘要 |
A lipid membrane structure encapsulating an siRNA inside thereof and containing a lipid compound of the formula (I) as a lipid component (R 1 and R 2 represent CH 3 -(CH 2 ) n -CH=CH-CH 2 -CH=CH-(CH 2 ) m -, n represents an integer of 3 to 5, m represents an integer of 6 to 10, p represents an integer of 2 to 7, and R 3 and R 4 represent a C 1-4 alkyl group or a C 2-4 alkenyl group. |
| 申请公布号 |
EP3147277(A1) |
申请公布日期 |
2017.03.29 |
| 申请号 |
EP20150796352 |
申请日期 |
2015.05.18 |
| 申请人 |
National University Corporation Hokkaido University |
发明人 |
HARASHIMA, Hideyoshi;SATO, Yusuke;WARASHINA, Shota;HATAKEYAMA, Hiroto;HYODO, Mamoru;NAKAMURA, Takashi |
| 分类号 |
C07C215/08;A61K9/127;A61K31/7105;A61K35/12;A61K47/18;A61K48/00;A61P37/00;A61P43/00 |
主分类号 |
C07C215/08 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
