| 发明名称 | Acid-resistance in <i>Kluyveromyces marxianus </i>by engineering transcriptional factor | ||
| 摘要 | A microorganism with improved acid-resistance. A microorganism capable of efficiently producing 3-HP, and methods for producing an organic acid. | ||
| 申请公布号 | US9605284(B2) | 申请公布日期 | 2017.03.28 |
| 申请号 | US201414531508 | 申请日期 | 2014.11.03 |
| 申请人 | SAMSUNG ELECTRONICS CO., LTD. | 发明人 | Lee Juyoung;Koo Hyunmin;Park Jaechan;Kim Jieun;Kim Jinha;Park Joonsong;Chung Soonchun;Cho Byungkwan |
| 分类号 | C12P7/42;C07K14/39;C07K14/47;C12N9/12;C12P7/18;C12P7/46;C12P7/56 | 主分类号 | C12P7/42 |
| 代理机构 | Leydig, Voit & Mayer, Ltd. | 代理人 | Leydig, Voit & Mayer, Ltd. |
| 主权项 | 1. A recombinant Kluyveromyces marxianus yeast cell comprising a gene encoding a mutated subunit of the RNA polymerase II (RNAP II) complex, wherein the mutated subunit increases the acid resistance of the yeast cell, and the mutated subunit is a mutated TATA-box binding protein (TBP) comprising a sequence selected from the group consisting of SEQ ID NO: 2, 3, and 4. | ||
| 地址 | Suwon-si KR | ||