发明名称 |
Methods and biocompatible compositions to achieve sustained drug release in the eye |
摘要 |
A nanostructured biocompatible wafer for placement in the conjunctival cul-de-sac. The wafer contains a tissue-reactive mucoadhesive polymer and a mesh formed of a plurality of hydrophobic polymer fibers. Also provided is a method for treating glaucoma, an ocular surface disorder, or an ocular surface infection using the nanostructured biocompatible wafer. Additionally, an injectable sustained-release formulation for treating an ocular disorder is disclosed. The formulation includes a drug contained within a plurality of microparticles formed of a biodegradable polymer and are coated with a tissue-reactive compound. Further provided is a method for treating an ocular disorder by injecting the microparticulate sustained release formulation. |
申请公布号 |
AU2015311637(A1) |
申请公布日期 |
2017.03.23 |
申请号 |
AU20150311637 |
申请日期 |
2015.09.08 |
申请人 |
Integral Biosystems LLC |
发明人 |
Barman, Shikha P.;Liu, Moli;Barman, Koushik;Ward, Kevin L.;Hackett, Brendan |
分类号 |
A61F2/00 |
主分类号 |
A61F2/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|