The disclosure provides polynucleotides encoding a polypeptide including a morpholino linker. In some embodiments, the polynucleotides of the invention have increased stability compared to wild-type polynucleotides.
申请公布号
WO2017049286(A1)
申请公布日期
2017.03.23
申请号
WO2016US52482
申请日期
2016.09.19
申请人
MODERNA THERAPEUTICS, INC.
发明人
BUTORA, Gabor;FRALEY, Andrew, W.;MIRACCO, Edward, John;NELSON, Jennifer;RHODEN-SMITH, Amy;STANTON, Matthew