发明名称 TRUNCATED HER2 SRM/MRM ASSAY
摘要 The present invention is related to a method for measuring the level of Her2 protein and truncated Her2 protein in a protein digest prepared from a biological sample of formalin-fixed tissue, comprising detecting and quantifying a peptide derived from the intracellular domain of Her2 in said protein digest prepared from said biological sample using mass spectrometry; and calculating the level of Her2 protein and truncated Her2 protein in said sample, wherein said peptide is the peptide of SEQ ID NO:7 and wherein said level is an absolute level of both versions of the Her2 protein.
申请公布号 EP3144394(A1) 申请公布日期 2017.03.22
申请号 EP20160195288 申请日期 2011.12.08
申请人 Expression Pathology, Inc. 发明人 Krizman, David B.
分类号 C12Q1/02 主分类号 C12Q1/02
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