发明名称 |
2-ARYL IMIDAZO[1,2-A]PYRIDINE-3-ACETAMIDE DERIVATIVES, PREPARATION METHODS AND USE THEREOF |
摘要 |
Disclosed are 2-arylimidazo[1,2-a]pyridine-3-acetamide derivatives represented by formula I, their tautomer, racemate or optical isomer, their pharmaceutically acceptable salt, or their solvates, wherein R 1 , R 2 , R 3 and R 4 are defined as in the specification. Preparation methods of said compounds and use of said compounds in treating and/or preventing central nervous system disease associated with TSPO functional disorder |
申请公布号 |
EP2586780(B1) |
申请公布日期 |
2017.03.22 |
申请号 |
EP20110797579 |
申请日期 |
2011.06.09 |
申请人 |
Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China |
发明人 |
YANG, Ri fang;LI, Yun feng;LI, Yong zhen;ZHAO, Nan;YUN, Liu hong;QIN, Juan juan;FENG, Zhong yao;ZHANG, You zhi |
分类号 |
C07D471/04;A61K31/437;A61P25/00 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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