发明名称 NON-NATURAL AMINO ACID tRNA SYNTHETASES FOR PYRIDYL TETRAZINE
摘要 The invention provides methods and compositions for a mutein aminoacyl-tRNA synthetase that preferentially charges a tRNA with a non-natural amino acid. Also provided are methods for incorporating the non-natural amino acids, pyridinyl-amino tetrazine amino acids, into a protein, and further conjugating a biologically active adduct to the pyridinyl-amino tetrazine.
申请公布号 EP3055320(A4) 申请公布日期 2017.03.22
申请号 EP20140851807 申请日期 2014.10.10
申请人 Sutro Biopharma, Inc. 发明人 ZIMMERMAN, Erik S.;THANOS, Christopher
分类号 C12N9/00;C12N15/52 主分类号 C12N9/00
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