发明名称 mutantes de fc do anticorpo resistentes a protease ativa
摘要 The present invention relates to modified Fc-containing molecules including modified antibodies characterized by increased resistance to host and pathogen-derived proteases, ability to interact with FcγR receptors except with FcγRI, and lack of induction of IL-10 secretion by macrophages, and methods of using and making them.
申请公布号 BR112013018317(A2) 申请公布日期 2017.03.21
申请号 BR20131118317 申请日期 2011.12.15
申请人 JANSSEN BIOTECH, INC. 发明人 RANDALL BREZSKI;ROBERT JORDAN;WILLIAM STROHL
分类号 A61K39/00 主分类号 A61K39/00
代理机构 代理人
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