发明名称 |
COMPOSITIONS AND METHODS FOR GROWTH FACTOR MODULATION |
摘要 |
Provided herein are proteins, antibodies, assays and methods useful for modulating growth factor levels and/or activities. In some embodiments, such growth factors are members of the TGF-β superfamily of proteins. |
申请公布号 |
US2017073406(A1) |
申请公布日期 |
2017.03.16 |
申请号 |
US201515309141 |
申请日期 |
2015.05.06 |
申请人 |
SCHOLAR ROCK, INC. |
发明人 |
Schurpf Thomas;Chang Gregory P.;Mahanthappa Nagesh K. |
分类号 |
C07K16/22;A61K38/18 |
主分类号 |
C07K16/22 |
代理机构 |
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代理人 |
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主权项 |
1. A method of increasing the level of free growth factor in a biological system comprising contacting said biological system with antibody MAB246 and/or MAB2463 and/or a fragment thereof. |
地址 |
Cambridge MA US |