CRISPR/CAS-RELATED METHODS AND COMPOSITIONS FOR TREATING HERPES SIMPLEX VIRUS TYPE 1 (HSV-1)

摘要

CRISPR/CAS-related compositions and methods for treatment of HSV-1 are disclosed.

主权项

1. A CRISPR/Cas system, comprising:
a gRNA molecule comprising a targeting domain which is complementary with a target sequence of a herpes simplex virus (HSV) viral gene selected from the group consisting of a UL19 gene, a UL30 gene, a UL48 gene, and a UL54 gene; and a Cas9 molecule.