Disclosed is a double-stranded oligonucleotide decoy which includes two types of transcription factor binding sites and yet is small in size. The double-stranded oligonucleotide decoy according to the present invention having binding affinity to two types of transcription factors includes a first binding site for a first transcription factor, and a second binding site for a second transcription factor. A first strand including a sense strand of the first binding site and a second strand including a sense strand of the second binding site hybridize to form a double strand, and the sense strand of the first binding site and the sense strand of the second binding site are at least partially hybridized.