发明名称 |
Particles for use in a pharmaceutical composition |
摘要 |
The invention provides a method of making a composition for inhalation which includes the step of mixing particles of additive material having a diameter of not more than 2 μm with active particles, wherein the additive material is suitable for promoting the dispersal of active particles upon aerolization of a dry powder in a dry powder inhaler. |
申请公布号 |
US9585839(B2) |
申请公布日期 |
2017.03.07 |
申请号 |
US201314050819 |
申请日期 |
2013.10.10 |
申请人 |
VECTURA LIMITED |
发明人 |
Staniforth John Nicholas;Morton David Alexander Vodden |
分类号 |
A61K9/14;A61K9/00;A61K9/16 |
主分类号 |
A61K9/14 |
代理机构 |
Reed Smith LLP |
代理人 |
Gibson Matthew S.;Reed Smith LLP |
主权项 |
1. A method of making a composition for inhalation which includes the step of mixing particles of additive material having a diameter of not more than 2 μm with active particles, wherein the additive material is suitable for promoting the dispersal of active particles upon aerolisation of a dry powder in a dry powder inhaler, and the step of pressing the particles of additive material to the surfaces of the active particles by a milling step involving compressing the mixture of active and additive particles in a gap of fixed predetermined width, wherein the additive comprises magnesium stearate. |
地址 |
Chippenham, Wiltshire GB |