发明名称 Particles for use in a pharmaceutical composition
摘要 The invention provides a method of making a composition for inhalation which includes the step of mixing particles of additive material having a diameter of not more than 2 μm with active particles, wherein the additive material is suitable for promoting the dispersal of active particles upon aerolization of a dry powder in a dry powder inhaler.
申请公布号 US9585839(B2) 申请公布日期 2017.03.07
申请号 US201314050819 申请日期 2013.10.10
申请人 VECTURA LIMITED 发明人 Staniforth John Nicholas;Morton David Alexander Vodden
分类号 A61K9/14;A61K9/00;A61K9/16 主分类号 A61K9/14
代理机构 Reed Smith LLP 代理人 Gibson Matthew S.;Reed Smith LLP
主权项 1. A method of making a composition for inhalation which includes the step of mixing particles of additive material having a diameter of not more than 2 μm with active particles, wherein the additive material is suitable for promoting the dispersal of active particles upon aerolisation of a dry powder in a dry powder inhaler, and the step of pressing the particles of additive material to the surfaces of the active particles by a milling step involving compressing the mixture of active and additive particles in a gap of fixed predetermined width, wherein the additive comprises magnesium stearate.
地址 Chippenham, Wiltshire GB