Bone implant device

摘要

An osteoimplant device is provided. The osteoimplant device includes a body of nondemineralized cortical bone and an outer surface having at least one region including demineralized bone. The osteoimplant device is formable into a shape and size configured for implantation at a surgical site. A disc shaped osteoimplant can be used for a facet joint fusion. A method of treating a patient having a bone defect in a host bone is also provided, the method including inserting the osteoimplant into the bone defect, for example, one associated with a facet joint.

主权项

1. An osteoimplant device comprising: a body, which comprises a nondemineralized cortical bone, the nondemineralized cortical bone body includes a disc and at least one region comprising an enzymatically modified and ionically charged demineralized bone comprising a regular or irregular shape comprising an annular periphery, a substantially crescent shape periphery, a substantially semicircular shape periphery, a substantially O shape periphery or combinations thereof, wherein the implant device is formable into a shape and size configured for implantation at a surgical site, and wherein the at least one region of demineralized bone comprises demineralized bone fibers and demineralized bone chips in a ratio of from about 25:75 to about 75:25 fibers to chips and at a depth of from about 50 microns to about 5000 microns, and the osteoimplant comprises a compressive modulus of from about 2,000 MPa to 3,800 MPa and exhibits resiliency and flexibility of from about 10 degree to about 45 degree angles.