发明名称 Neprilysin hæmmere
摘要 In one aspect, the invention relates to compounds having the formula: where X, Ra, Rb, R2, and R7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds are prodrugs of compounds having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds.
申请公布号 DK2882716(T3) 申请公布日期 2017.03.06
申请号 DK20130750454T 申请日期 2013.08.07
申请人 Theravance Biopharma R&D IP, LLC 发明人 FLEURY, Melissa;HUGHES, Adam D.
分类号 C07D231/14;A61K31/415;A61K31/4192;A61K31/42;A61K31/421;A61P9/12;C07D249/04;C07D261/18;C07D263/38;C07D405/12 主分类号 C07D231/14
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