| 摘要 |
Provided is a method for producing an aromatic compound, e.g., salicylic acid, and a derivative thereof with high productivity using a microorganism. Provided are: a method for producing a microorganism having a modified sugar metabolic pathway, said method comprising introducing, into a microorganism, one or multiple genes each encoding an enzyme which can inhibit the expression of a phosphotransferase-type enzyme-encoding gene in the microorganism, can inhibit the expression of a pyruvate kinase-encoding gene in the microorganism, and enables the microorganism to synthesize the aromatic compound from chorismic acid or isochorismic acid; a genetically modified microorganism produced by the method; and a method for producing an aromatic compound and a derivative thereof, said method comprising culturing the microorganism and then collecting the aromatic compound and the like from the liquid culture. |
