Crystal Form of Quinoline Compound and Process for its Production

摘要

H:/dr/lntenvovn/NRPortbl/DCC/RBR/5067473_ .DOC- 1/04/2013 A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) 5 represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.