发明名称 |
ANTITUMOR NAPHTHALENYL BENZAMIDE DERIVATIVES |
摘要 |
Naphthalenyl benzamide derivatives according to formula I;;are described, wherein Ar is an aryl or heteroaryl group, and R1-R4 are independently selected from H, halogen, CF3, hydroxyl, C1-C4 alkyl, and C1-C4 oxyalkyl, or a pharmaceutically acceptable salt thereof. The naphthalenyl benzamide derivatives can be used for the treatment of cancer in a subject. |
申请公布号 |
US2017057910(A1) |
申请公布日期 |
2017.03.02 |
申请号 |
US201615249981 |
申请日期 |
2016.08.29 |
申请人 |
THE CLEVELAND CLINIC FOUNDATION |
发明人 |
Reu Frederic J.;Vatolin Sergei;Phillips James G.;Grabowski Dale;Jha Babal Kant |
分类号 |
C07C233/65 |
主分类号 |
C07C233/65 |
代理机构 |
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代理人 |
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主权项 |
1. A compound of formula I wherein Ar is an aryl or heteroaryl group, and R1-R4 are independently selected from H, halogen, CF3, hydroxyl, C1-C4 alkyl, and C1-C4 oxyalkyl, or a pharmaceutically acceptable salt thereof. |
地址 |
Cleveland OH US |