发明名称 ANTITUMOR NAPHTHALENYL BENZAMIDE DERIVATIVES
摘要 Naphthalenyl benzamide derivatives according to formula I;;are described, wherein Ar is an aryl or heteroaryl group, and R1-R4 are independently selected from H, halogen, CF3, hydroxyl, C1-C4 alkyl, and C1-C4 oxyalkyl, or a pharmaceutically acceptable salt thereof. The naphthalenyl benzamide derivatives can be used for the treatment of cancer in a subject.
申请公布号 US2017057910(A1) 申请公布日期 2017.03.02
申请号 US201615249981 申请日期 2016.08.29
申请人 THE CLEVELAND CLINIC FOUNDATION 发明人 Reu Frederic J.;Vatolin Sergei;Phillips James G.;Grabowski Dale;Jha Babal Kant
分类号 C07C233/65 主分类号 C07C233/65
代理机构 代理人
主权项 1. A compound of formula I wherein Ar is an aryl or heteroaryl group, and R1-R4 are independently selected from H, halogen, CF3, hydroxyl, C1-C4 alkyl, and C1-C4 oxyalkyl, or a pharmaceutically acceptable salt thereof.
地址 Cleveland OH US