| 发明名称 |
IMMUNE CELLS HAVING INCREASED IMMUNITY OR RESISTANCE TO AN IMMUNOSUPPRESSIVE CYTOKINE AND USE OF THE SAME |
| 摘要 |
Provided herein are immune cells having increased immunity or resistance to an immunosuppressive cytokine and use of the same. |
| 申请公布号 |
US2017056448(A1) |
申请公布日期 |
2017.03.02 |
| 申请号 |
US201615253215 |
申请日期 |
2016.08.31 |
| 申请人 |
IFM THERAPEUTICS, INC |
发明人 |
Glick Gary D.;Franchi Luigi |
| 分类号 |
A61K35/17;G01N33/50;C12N5/0783;C07K16/18;C07K14/725 |
主分类号 |
A61K35/17 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of increasing resistance of a T cell or an innate immune cell to at least one immunosuppressive cytokine, the method comprising:
(a) providing a T cell or an innate immune cell, and (b) culturing the T cell or the innate immune cell in a culture medium comprising an amount of an NLRP3 activator sufficient to increase resistance of a T cell or an innate immune cell to the at least one immunosuppressive cytokine. |
| 地址 |
Cambridge MA US |
