| 发明名称 |
MODULATION OF SYNAPTIC MAINTENANCE |
| 摘要 |
C1q is shown to be expressed in neurons, where it acts as a signal for synapse elimination. Methods are provided for protecting or treating an individual suffering from adverse effects of synapse loss. These findings have broad implications for a variety of clinical conditions, including Alzheimer's disease. |
| 申请公布号 |
US2017059559(A1) |
申请公布日期 |
2017.03.02 |
| 申请号 |
US201615349889 |
申请日期 |
2016.11.11 |
| 申请人 |
The Board of Trustees of the Leland Stanford Junior University |
发明人 |
Barres Ben A.;Stevens Beth A. |
| 分类号 |
G01N33/50;A61K48/00 |
主分类号 |
G01N33/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of inhibiting synapse loss comprising the step of:
administering a therapeutic amount of a complement inhibitor to a patient suffering from adverse synapse loss. |
| 地址 |
Stanford CA US |
