发明名称 IGF-1R ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER
摘要 The present invention relates to an antibody-drug-conjugate capable of binding IGF-1R. From one aspect, the invention relates to an antibody-drug-conjugate comprising an antibody capable of binding to IGF-1R, said antibody being conjugated to at least one drug selected from derivatives of dolastatin 10 and auristatins. The invention also comprises method of treatment and the use of said antibody-drug-conjugate for the treatment of cancer.
申请公布号 EP3134124(A1) 申请公布日期 2017.03.01
申请号 EP20150720045 申请日期 2015.04.27
申请人 Pierre Fabre Médicament 发明人 RILATT, Ian;PEREZ, Michel;GOETSCH, Liliane;BROUSSAS, Matthieu;BEAU-LARVOR, Charlotte;HAEUW, Jean-François;CHAMPION, Thierry;ROBERT, Alain
分类号 A61K47/50;A61P35/00 主分类号 A61K47/50
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