发明名称 |
INCREASING PROTEIN PRODUCTION BY INCREASING ABC50 EXPRESSION OR ACTIVITY |
摘要 |
The disclosure provides methods and materials for increasing the expression of a protein of interest such as an antibody by a cell ABC50 expression or activity is increased which increases expression of the protein or antibody of interest. The disclosure also provides methods and materials for increasing the sensitivity of a cell to an endoplasmic reticulum stress agent such as Econazole by decreasing the level of ABC50. |
申请公布号 |
EP2427556(B1) |
申请公布日期 |
2017.03.01 |
申请号 |
EP20100771937 |
申请日期 |
2010.05.05 |
申请人 |
University Health Network |
发明人 |
BERGER, Stuart, A. |
分类号 |
C12N15/63;C07K16/00;C12N15/113;C12N15/12;C12N15/67;C12N15/867;C12P21/02;C12P21/08 |
主分类号 |
C12N15/63 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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