发明名称 Spiro-lactam NMDA receptor modulators and uses thereof
摘要 Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
申请公布号 US9579304(B2) 申请公布日期 2017.02.28
申请号 US201615049577 申请日期 2016.02.22
申请人 Aptinyx, Inc. 发明人 Lowe, III John A.;Khan M. Amin
分类号 A61K31/397;C07D487/10 主分类号 A61K31/397
代理机构 Goodwin Procter LLP 代理人 Goodwin Procter LLP
主权项 1. A compound represented by: and stereoisomers and pharmaceutically acceptable salts thereof.
地址 Evanston IL US